The Lancet published an article (31/07/24) which provides a comprehensive overview of the current state of knowledge and challenges surrounding Long Covid, also known as post-COVID-19 condition. The article found that Long Covid, defined as symptoms persisting for 3 months or more after acute COVID-19, affects multiple organ systems and poses a significant burden on individuals, healthcare systems, and economies. Despite extensive research, clinicians face challenges in evaluating and managing Long Covid due to conflicting definitions, multiple pathophysiological mechanisms, lack of a universal biomarker, and evolving nature of the condition.
The article identifies several priority areas for future Long Covid research, including genetic and epigenetic studies, biomarker development, next-generation clinical trials, and optimizing rehabilitation protocols and health services. Vaccine research is emphasized, particularly investigating protein-based vaccines for protection against reinfection and potential Long Covid exacerbation. The authors stress the importance of bridging the gap between biological mechanisms and clinical management through targeted research to address what has been described as the “mass disabling event” of Long Covid .
The full article can be read here. You can see one of the author’s twitter thread about the article here.
Durham County Department of Public Health have produced a great video demonstrating that covid and many other viruses are airborne. The video is less than two minutes long. An airborne virus is a virus that can infect other people through particles in the air, sometimes for hours after the sick person has left the area! […]
This narrative review shows that POTS, ME/CFS and Long COVID are closely related conditions that share common biological mechanisms. The authors explain that problems with the autonomic nervous system, immune dysregulation and autoimmunity, mitochondrial dysfunction, reduced blood flow to the brain, and neuroinflammation all play a role. POTS and ME/CFS are identified as the most […]
Summary: Comparing Long Covid symptoms between patients that received COVID-19 vaccinations and those that did not. Study by Pasculli et. al., (2025) summarised by Amanda Harrington-Vail Introduction Since the COVID-19 pandemic was officially declared, almost 780 million cases and nearly 7 million deaths have been reported worldwide. Although COVID-19 vaccination has reduced the risk of […]
